000			03248nabaa22003852ab4500
003			INSP
005			20230509130426.0
008			230504c2022 mx ||||oo||||||0| 0 eng d
024			_2DOI _a10.1016/j.numecd.2022.06.021
040			_aINSP _bspa _cINSP _eAACR
041			_aeng
245			_aSugar- and artificially-sweetened soda consumption and subclinical atherosclerosis among Mexican women
336			_atexto
337			_acomputadora
338			_aelectrónico
340			_aArchivo _mPDF
520			_aAbstract Background and aims: Sugar-sweetened soda consumption is associated with most cardiometabolic risk factors. The role of artificially-sweetened beverages in cardiovascular disease (CVD) is inconclusive, but their consumption correlates with health impairment. Little is known about the contribution of soda consumption in subclinical stages of atherosclerosis. Therefore, we evaluated the relation between sugar- and artificially-sweetened soda consumption and carotid intima-media thickness (IMT) among Mexican women. Methods and results: We cross-sectionally evaluated 1093 women enrolled in the Mexican Teachers' Cohort who were free of CVD, diabetes or cancer. Sugar- and artificially-sweetened soda consumption was estimated from a validated 140-item food frequency questionnaire in 2008 and all women underwent a carotid ultrasound assessment three years later. Participants were categorized into tertiles of soda consumption in servings/week. Subclinical atherosclerosis was defined as a mean left and/or right IMT ≥0.8 mm or the presence of plaque on either common carotid artery. In multivariable regression models, women in the highest tertile of sugar-sweetened soda consumption had 2.6% (95%CI: 0.8, 4.5) mean increased IMT, and had 2-fold the risk of carotid atherosclerosis (PR: 2.0, 95%CI: 1.3, 3.2) compared to those in the lowest tertile. In stratified analyses, older and postmenopausal women who consumed sugar-sweetened soda had an increased IMT and atherosclerosis risk. Artificially-sweetened soda consumption was not associated with IMT or carotid atherosclerosis. Conclusions: Sugar-sweetened soda consumption was associated with subclinical atherosclerosis among disease-free Mexican women. Public health strategies to decrease CVD should consider the impact of sugar-sweetened soda consumption, particularly in older women.
650		0	_910839 _aBebidas Endulzadas Artificialmente
650		7	_91606 _aEnfermedades Cardiovasculares
650		0	_910840 _aEnfermedades de las Arterias Carótidas
650		0	_910841 _aGrosor Intima-Media Carotídeo
700			_aCortés Valencia, Adrian _eautor
700			_aArvizu, Mariel _ecoautor
700			_aMonge, Adriana, _ecoautor
700			_aOrtiz Panozo, Jorge Eduardo, _cDr. _uCISP/INSP
700			_aLópez Ridaura, Ruy, _cDr. _ecoautor
700			_aCantú Brito, Carlos, _ecoautor
700			_aChavarro, Jorge, _ecoautor
700			_aCatzin Kuhlmann, Andrés, _ecoautor
700			_aFagherazzi, Guy, _ecoautor
700			_aYunes Díaz, Elsa María, _ecoautor
700			_aLajous Loaeza, Martín _ecoautor
773			_aNutrition, Metabolism & Cardiovascular _gvol. 32, número 9, 2022 2052-2060
942			_2ddc _cART
999			_c20094 _d20094